A significant but not ridiculously high dose of vitamin B5 makes the immune system more aggressive towards Mycobacterium tuberculosis tuberculosis bacteria. This is suggested by an animal study that Chinese immunologists from the University of Guangzhou have published in Frontiers in Immunology.
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Researchers experimented with mice by placing 200 bacteria of the M37R strain in their lungs, the M. tuberculosis H37Rv. Mycobacterium tuberculosis strain H37Rv is a variant of TB bacteria with which scientists have experimented since the beginning of the 20th century. The estimated dose of vitamin B5 was 500-700 mg. This is not a very high dose. In most online stores with supplements you can easily get those that contain 500 mg in a capsule.
After four weeks, researchers investigated that there are fewer TB TB bacteria in the lungs of mice. In contrast to the control group, which was not given vitamin B5. How the vitamin B5 works on tuberculosis bacteria scientists discovered when they examined the immune cells in the blood of mice. Vitamin B5 did not increase the number of immune cells, but caused CD4-T cells to produce more cytokines, such as interleukin-17 and interferon-gamma.
In conclusion, research suggests that orally administered vitamin B5 significantly inhibits the growth of Mycobacterium tuberculosis by regulating innate and adaptive immunity. It can therefore have therapeutic properties in the clinical treatment of tuberculosis.
You can read also: P5P – highly bioavailable form of vitamin B6