Neurotransmitters are substances responsible for improving the function of the nervous system. Their aim is to improve the transmission of information from the “headquarters” to the executive apparatus. One of them is glycine – an amino acid that is part of numerous supplements. If you want to learn more about this relationship, read the following text.
Glycine – general information
Under the above name, there is an organic chemical compound that belongs to the group of standard biogenic amino acids. He is considered the simplest relationship with the group mentioned. Glycine is also a neurotransmitter – a substance responsible for mediating signal transmission from the central nervous system.
Glycine is also an endogenous compound. It means that our body is capable of its own synthesis. Production may occur from substances such as alanine, choline, glycosalate, glutamate or serine. In addition, it can be found in proteins (where it is as much as 7.2%), as well as in collagen. In the case of the latter, glycine is more than 30% of all amino acids that make it.
Glycine is also found in natural food, both in animal and vegetable products. It turns out that a varied diet will be an ideal solution to ensure constant supplementation with this amino acid
Properties of glycine
Glycine is a compound that affects the functioning of the nervous system. Therefore, he is responsible for reducing the signs of depression and improves the quality of sleep. Improving the transmission of signals to the nervous system not only improves its functioning, but also has a positive effect on concentration and memory.
In addition to the effects on the nervous system, glycine has a number of other advantages. In professional literature, it is most often mentioned
– participation in the synthesis of erythrocytes, hemoglobin and nucleic acid components;
– presence in the detoxification processes of the body;
– participation in glucose and creatine biosynthesis;
– anti-contraction and anti-inflammatory effect.
Glycine is also a substance that is successfully used in medicine. It is used for cases such as ulcers, contusions, prostate problems, benign prostatic hypertrophy, degenerative disease, kidney disease, and is one of the elements of cancer prevention.
Glycine is a substance that does not occur alone. However, it is an ingredient of numerous supplements currently offered on the market. Very often it can be found in the composition of testosterone boosters, creatine stacks, amino acid mixtures or carbohydrate-protein products.
It is assumed that glycine supplementation should be from 1 to 3 g of the product containing it in its composition. In the case of treatment of osteoarthritis, two doses of the preparation should be used at a rate of 5 g, where each portion should be taken in the morning and in the evening. In turn, in the treatment of benign prostatic hyperplasia, it is recommended to use from 390 to 780 mg of glycine in the form of a properly composed diet.
Symptoms of improper supplementation
Glycine deficiencies are very rare due to the body’s ability to synthesize independently. Shortages are noted in the case of long-term and high protein deficiencies in the diet and diseases that accompany it
The most common symptoms of abnormal supplementation that usually results from exceeding the allowed doses are diarrhea, nausea, drowsiness and vomiting. It is also worth mentioning the real threat in the case of people suffering from schizophrenia. There is verified evidence of the adverse effects of glycine combined with a drug called clozapine, which is used during the treatment of this disease.
A 2011 study, conducted in Poland, aimed to prove the benefits of using glycine in anti-psychotic therapy. The research material was a group of 32 patients (3 people dropped out during the tests) aged 18 to 55 years. The experiment lasted 10 weeks and was divided into three parts.
The first one lasted 14 days and during its lifetime the patients’ mental stability was monitored. Over the next six weeks, supplementation was carried out with a glycine preparation at a dose of 60 g a day (previously used drugs were administered in unchanged amounts). third and the last part took place two weeks after the end of taking glycine. Her goal was to assess the mental state and the effects obtained.
The results of the study confirmed the effectiveness of using glycine in psychiatric therapy. Symptoms have been alleviated, and only 5 patients have experienced the appearance of unwanted symptoms in the form of nausea.